Medplexus

Are glycoprotein belonging to Immunoglobulin superfamily. Large 'Y' shaped protein produced by B- Lymphocyte. It neutralize foreing object such as bacteria, virus,Fungus etc. Has Antigen binding site. Contain two heavy(H) chain and two light (L) chain. Each heavy chain consists of about 450 amino acids and  each light chain consists of about 220 amino acids. Disulfide bond hold each light chain to heavy chain. This part of Antibodies is more flexible so it is called Hinge Region .Beyond the hinge region, part of the two heavy chain form stem region. Most Antibodies have two antigen binding site, thay are said to be bivalent. Each antibody has a variable region at the top of the arms Types of  Immunoglobulin are: IgG 1. Found in all fluid, smallest but most common Antibodies (70 - 80%). 2. Monomer structure 3. Very important for fight againest the bacteria and virus. 4. Can cross the placenta. IgM 1. Largest antibody. 2.  Found in the blood and lymph fluid, are the first type o